I just downloaded this software. I also downloaded a preset and when I launch the game Blade and Soul I noticed some text in the upper left corner of the screen signifying that SFX has started but I don't know how to configured it or use a preset. Please help.

First off, you need to remove the extra naming on the file, it should only be named SweetFX_settings. Second, you have replace the file in the SweetFX folder with the one you just downloaded and renamed.

Have you tried turning it off then on again?

Is it sweetfx or ReShade?